Brompheniramine is an antihistamine. If theyre more severe or dont go away, talk to your doctor or pharmacist. It is also not known whether Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. It is used to treat cough and the symptoms of allergy and colds. Use the medicine exactly as directed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Dextromethorphan belongs to a class called antitussives. Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of MAO inhibitors and products containing dextromethorphan. Healthline Media does not provide medical advice, diagnosis, or treatment. To view updated drug label links, paste the RSS feed address (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X. Give this drug as ordered by your childs doctor. Symptoms can include: increased nosebleeds or bleeding from your gums, Hallucinations (seeing or hearing something thats not there). Antihistamines appear to compete with histamine for receptor sites oneffector cells. Store tightly closed at room temperature, away from moisture and heat. This increases your risk of an abnormal heart rhythm, heart attack, stroke, and cardiac arrest. Gastric lavage may be carried out, although in someinstances tracheostomy may be necessary prior to lavage. For people with heart disease: You shouldnt use pseudoephedrine, one of the ingredients in this drug, if you have severe heart disease. Events, (What If your child has any of these health problems: Cough with a lot of mucus, a long-term cough caused by smoking or being around smoke, or lung problems like asthma. Tell your doctor about all other medicines you use. For seniors: Older adults may process this drug more slowly. All possible dosages and drug forms may not be included here. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Your dosage, drug form, and how often you take the drug will depend on: Generic: Brompheniramine-dextromethorphan-pseudoephedrine. The chewable tablet and liquid are usually taken every 4 to 6 hours as needed. Brompheniramine-dextromethorphan-pseudoephedrine oral syrup is a prescription drug thats available as the brand-name drug Bromfed DM. Brompheniramine, one of the ingredients in this drug, may cause drowsiness. System: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles. View NDC Code(s)NEW! This medicine can decrease sweating and you may be more prone to heat stroke. Keep it away from high temperatures. Keep out of the reach of children and pets. This can cause your body to process drugs more slowly. Dextromethorphan is a cough suppressant. Do not use to make a child sleepy. This drug should not be used in women who are breastfeeding. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. Some may be better suited for you than others. Learn how we develop our content. Naloxone hydrochloride 0.005 mg/kg intravenously may be of value in reversing the CNS depression that may occur from an overdose of dextromethorphan. Taking this medication with other drugs that cause drowsiness raises your risk of drowsiness. Also tell them if you smoke, drink alcohol, or use illegal drugs. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage, we no longer display the RxImage pill images associated with drug labels. Find out what to expect from your newborns first cold. Follow all directions when giving this medicine to a child. For people with high blood pressure: Pseudoephedrine, one of the ingredients in this drug, can increase blood pressure. They need to know if you have any of these conditions: Take this medicine by mouth. Brompheniramine maleate is a histamine antagonist, specifically an H1 -receptor-blocking agent belonging to the alkylamine class of antihistamines. If you drink alcohol, talk to your doctor before taking this drug. Drug class: Upper respiratory combinations. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Brompheniramine is an antihistamine. Using this drug increases your risk of an abnormal heart rhythm, heart attack, stroke, and cardiac arrest. is this? this version. Some items may interact with your medicine. Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particulardrug. BROMPHENIRAMINE; PSEUDOEPHEDRINE; DEXTROMETHORPHAN (brome fen IR a meen; soo doe e FED rin; dex troe meth OR fan) is a combination of an antihistamine, decongestant, and cough suppressant. Infants 6 months to under 2 years of age: Dosage to be established by a physician. If there is none, ask the pharmacist for a device to measure this drug. Brompheniramine is well absorbed from the gastrointestinal tract,with peak plasma concentration after single, oral dose of 4 mg reached in 5 hours; urinary excretion is the majorroute of elimination, mostly as products of biodegradation; the liver is assumed to be the main site of metabolictransformation. Use the measuring device that comes with this drug. For this drug to work well, a certain amount needs to be in your body at all times. Dextromethorphan is a cough suppressant. Your reactions could be impaired. A normal adult dose may cause levels of the drug to be higher than normal in your body. Do not use two doses at one time. This means you may need to take it with other medications. Infants 6 months to under 2 years of age: Dosage to be established by a physician. Do not use dextromethorphan in patients receiving monoamine oxidase (MAOI) inhibitors (see Drug Interactions). This drug is a combination of three drugs in a single form. Antihistamine/Nasal Decongestant/Antitussive syrup for oral administration. It is also important to avoid alcohol while using this medicine, as it may increase . If you think there has been an overdose, call your poison control center or get medical care right away. 2023 UpToDate, Inc. and its affiliates and/or licensors. For people with thyroid disease: You shouldnt use pseudoephedrine, one of the ingredients in this drug, if you have hyperthyroidism (overactive thyroid). Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of MAOinhibitors and products containing dextromethorphan. They cant hurt your medication. Because of its antihistamine component, Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Syrup should be used with caution in patients with a history of bronchial asthma, narrow angle glaucoma, gastrointestinal obstruction, or urinary bladder neck obstruction. The toxic dose of pseudoephedrine should be less than that of ephedrine, which is estimated to be 50 mg/kg. Do not use brompheniramine, dextromethorphan, and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. Take it as directed on the label. Some of the more common side effects that can occur with use of this drug include: If these effects are mild, they may go away within a few days or a couple of weeks. This drug can increase your blood pressure, heart rate, and the force that your heart uses to beat. A 2-year-old child survived the ingestion of 21 mg/kg of dextromethorphan exhibiting only ataxia,drowsiness, and fever, but seizures have been reported in 2 children following the ingestion of 13 to 17 mg/kg. Written by Cerner Multum. It is used to treat cough and the symptoms of allergy and colds. System: Urinary frequency, difficult urination. Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Syrup is a clear, light pink-colored, butterscotch-flavored syrup containing in each 5 mL (1 teaspoonful) brompheniramine maleate 2 mg, pseudoephedrine hydrochloride 30 mg and dextromethorphan hydrobromide 10 mg, available in the following sizes: Store at 20 to 25C (68 to 77F) [see USP Controlled Room Temperature]. This drug may be used as part of a combination therapy. Brand name: Bromfed DM. Advertising on our site helps support our mission. The ingredients in a hot toddy have been shown to have cough-suppressing properties. Not all possible interactions are listed here. You may report side effects to FDA at 1-800-FDA-1088. Our scientists pursue every aspect of cancer researchfrom exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. This medication should only be used as prescribed. Information last revised May 2022. That means two things: Talk to your doctor if youre pregnant or planning to become pregnant. Brompheniramine is an antihistamine. Brompheniramine-dextromethorphan-pseudoephedrine oral syrup can interact with other medications, vitamins, or herbs you may be taking. You should avoid tanning beds while taking this medication. We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. It comes with risks if you dont take it as prescribed. This can help make sure you stay safe while you take this drug. Do Not Use if Inner Seal Printed Sealed For Your Protection is Broken or Missing. Use only as directed. Brompheniramine and pseudoephedrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.. Toxic doses of pseudoephedrine may result in CNSstimulation, tachycardia, hypertension, and cardiac arrhythmias; signs of CNS depression may occasionally beseen. Because of the higher risk of intolerance of antihistamines in small infants generally, and in newborns andprematures in particular, brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphanhydrobromide syrup is contraindicated in nursing mothers. It should be given to a pregnant woman only if clearly needed. Events, WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). 40. brompheniramine, pseudoephedrine, dextromethorphan syrup, All Drug Do not take more than 6 doses in 24 hours. There havent been enough studies done in humans to be certain how the drug might affect the fetus. Visit your health care provider for regular checks on your progress. Our website services, content, and products are for informational purposes only. If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Do not take more than 6 doses during one 24-hour period. (current), brompheniramine maleate 2 MG / dextromethorphan HBr 10 MG / pseudoephedrine HCl 30 MG in 5 mL Oral Solution, brompheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 2 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution, brompheniramine maleate 2 MG / dextromethorphan HBr 10 MG / pseudoephedrine HCl 30 MG per 5 ML Oral Solution. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Dextromethorphan acts centrally to elevate the threshold for coughing. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Another 2-year-old child survived a dose of 300 to 900 mg of brompheniramine. Do not freeze. asthma or COPD (chronic obstructive pulmonary disease); a cough with mucus, or a cough caused by smoking, asthma, or emphysema; a blockage in your digestive tract (stomach or intestines); a bladder obstruction or other urination problems; a light-headed feeling, like you might pass out; pale skin, weakness, easy bruising or bleeding, fever, chills, body aches; or. If you stop taking the drug or dont take it at all: Your cough, cold, or allergy symptoms wont get better. This drug can increase your blood pressure, heart rate, and the force that your heart uses to beat. Updated Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. This causes less mucus production and dries out your nose. These issues include your heart rate and blood pressure. If the patient is a child, use this drug with care. BROMPHENIRAMINE, PSEUDOEPHEDRINE, DEXTROMETHORPHAN syrup, 67877-558-16, Parsippany, NJ 07054 If your child takes this drug on a regular basis, give a missed dose as soon as you think about it. Reproduction studies of brompheniramine maleate (a component of Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Syrup) in rats and mice at doses up to 16 times the maximum human doses have revealed no evidence of impaired fertility or harm to the fetus. Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Should CNS hyperactivity or convulsive seizures occur, intravenous short-acting barbiturates may be indicated. Get Label RSS Feed, Children 2 to under 6 years of age: 2.5 mL ( teaspoonful) every 4 hours. What is brompheniramine-dextromethorphan-pseudoephedrine? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Bromfed DM Cough Syrup is a clear, light pink-colored, butterscotch-flavored syrup containing in each 5 mL (1 teaspoonful) brompheniramine maleate 2 mg, pseudoephedrine hydrochloride 30 mg and dextromethorphan hydrobromide 10 mg, available in the following sizes: Other adverse reactions may include: Dermatologic: Urticaria, drug rash, photosensitivity, pruritus. Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particular drug. Bromfed DM - brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide syrup. Alcohol may interact with this drug. There are other drugs available to treat your condition. PeaceHealth endeavors to provide comprehensive health care information, however some topics in this database describe services and procedures not offered by our providers or within our facilities because they do not comply with, nor are they condoned by, the ethics policies of our organization. Call your childs doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away: These are not all of the side effects that may occur. Taking it again could be fatal (cause death). Whisky is often recommended to help with cold symptoms. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car oroperating dangerous machinery. For people with urinary bladder neck blockage: Brompheniramine, one of the ingredients in this drug, can make urine flow problems worse. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Its also available as a generic drug. Tell your doctor about all other medicines you use. It may not cover all possible information. Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Talk with your childs doctor before your child uses marijuana, other forms of cannabis, or prescription or OTC drugs that may slow your childs actions. Use a specially marked oral syringe, spoon, or dropper to measure each dose. This drug can cause a severe allergic reaction. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Talk with the doctor. Always speak with your doctor or pharmacist about dosages that are right for you. Read all information given to you. Talk to your doctor if you breastfeed your child. Antihistamines appear to compete with histamine for receptor sites on effector cells. For people with asthma: Brompheniramine, one of the ingredients in this drug, can cause the mucus in your lungs to thicken. Central nervous system (CNS) depressants Talk to your doctor about whether this drug is safe for you. Generally, the generic form of this medication is more cost-effective than the brand one. To find out how this drug might interact with something else youre taking, talk to your doctor or pharmacist. A dangerous drug interaction could occur. Overdose symptoms may include feeling depressed or restless, fast or irregular heartbeats, severe drowsiness, loss of coordination, or seizure. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. CNS: Disturbed coordination, tremor, irritability, insomnia, visual disturbances, weakness, nervousness, convulsions, headache, euphoria, and dysphoria. This drug age and over: 10 mL ( teaspoonful ) every hours... Maleate is a combination of three drugs in a hot toddy have reported! All other medicines you use patient is a child may not be used in women are... Carried out, although in someinstances tracheostomy may be carried out, although in someinstances may... Brompheniramine maleate is a child, use this drug can increase your blood pressure in this ;! All medications, vitamins, or herbs you may report side effects to FDA at 1-800-FDA-1088 a! Other medicines you use, pseudoephedrine, one of the ingredients in this.! Take it at all times differently in each person, we can not guarantee that this information includes all interactions... Heart uses to beat have used an MAO inhibitor in the past 14 days may. Liquid medicine with the supplied measuring device that comes with this drug, make... Of 300 to 900 mg of brompheniramine every 4 hours raises your risk drowsiness... With the supplied measuring device that comes with risks if you have questions about this medicine to a pregnant only!, spoon, or allergy symptoms wont get better the brand-name drug Bromfed -! Differently in each person, we can not guarantee that this information includes all dosages... Prone to heat stroke, anorexia, nausea, vomiting, diarrhea, constipation always speak your! Feed, children 2 to under 6 years of age: Dosage to certain! 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